Donehower, Lawrence A. : rechercher sur Z-Library

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1

The Cancer Genome Atlas Pan-Cancer analysis project

Chang, Kyle, Creighton, Chad J, Davis, Caleb, Donehower, Lawrence, Drummond, Jennifer, Wheeler, David, Ally, Adrian, Balasundaram, Miruna, Birol, Inanc, Butterfield, Yaron S N, Chu, Andy, Chuah, Eric,

Journal:

Nature Genetics

Année:

2013

Langue:

english

Fichier:

PDF, 608 KB

english, 2013

2

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Donehower, Lawrence A., Harvey, Michele, Slagle, Betty L., McArthur, Mark J., Montgomery, Charles A., Butel, Janet S., Bradley,

Journal:

Année:

1992

Fichier:

PDF, 1.34 MB

1992

3

How does suppression of IGF-1 signaling by DNA damage affect aging and longevity?

George Hinkal, Lawrence A. Donehower

Journal:

Mechanisms of Ageing and Development

Année:

2008

Langue:

english

Fichier:

PDF, 510 KB

english, 2008

4

55K isoform of CDK9 associates with Ku70 and is involved in DNA repair

Hongbing Liu, Christine H. Herrmann, Karen Chiang, Tzu-Ling Sung, Sung-Hwan Moon, Lawrence A. Donehower, Andrew P. Rice

Journal:

Biochemical and Biophysical Research Communications

Année:

2010

Langue:

english

Fichier:

PDF, 722 KB

english, 2010

5

[ACM Press the 20th ACM SIGKDD international conference - New York, New York, USA (2014.08.24-2014.08.27)] Proceedings of the 20th ACM SIGKDD international conference on Knowledge discovery and data mining - KDD '14 - Automated hypothesis generation based on mining scientific literature

Spangler, Scott, Myers, Jeffrey N., Stanoi, Ioana, Kato, Linda, Lelescu, Ana, Labrie, Jacques J., Parikh, Neha, Lisewski, Andreas Martin, Donehower, Lawrence, Chen, Ying, Lichtarge, Olivier, Wilkins,

Année:

2014

Langue:

english

Fichier:

PDF, 2.22 MB

english, 2014

6

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

Totoki, Yasushi, Tatsuno, Kenji, Covington, Kyle R, Ueda, Hiroki, Creighton, Chad J, Kato, Mamoru, Tsuji, Shingo, Donehower, Lawrence A, Slagle, Betty L, Nakamura, Hiromi, Yamamoto, Shogo, Shinbrot, E

Journal:

Nature Genetics

Année:

2014

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2014

7

Exercise Effects on Tumorigenesis in a p53-Deficient Mouse Model of Breast Cancer

COLBERT, LISA H., WESTERLIND, KIM C., PERKINS, SUSAN N., HAINES, DIANA C., BERRIGAN, DAVID, DONEHOWER, LAWRENCE A., FUCHS-YOUNG, ROBIN, HURSTING, STEPHEN D.

Journal:

Medicine & Science in Sports & Exercise

Année:

2009

Langue:

english

Fichier:

PDF, 317 KB

english, 2009

8

Increased tumor cell proliferation in murine tumors with decreasing dosage of wild-type p53

Stuart D. Tyner, Jene Choi, Rodolfo Laucirica, Richard J. Ford, Lawrence A. Donehower

Journal:

Molecular Carcinogenesis

Année:

1999

Langue:

english

Fichier:

PDF, 832 KB

english, 1999

9

Effect of Intragastric Application of N-Methylnitrosourea in p53 Knockout Mice

Hiroko Ohgaki, Masakatsu Fukuda, Yasuo Tohma, Huatao Huang, George Stoica, Masae Tatematsu, Lawrence A. Donehower

Journal:

Molecular Carcinogenesis

Année:

2000

Langue:

english

Fichier:

PDF, 269 KB

english, 2000

10

Cooperation between Ha-ras and fos or transforming growth factor α overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis

Xiao-Jing Wang, David A. Greenhalgh, Lawrence A. Donehower, Dennis R. Roop

Journal:

Molecular Carcinogenesis

Année:

2000

Langue:

english

Fichier:

PDF, 245 KB

english, 2000

11

Suppression of thymic lymphomas and increased nonthymic lymphomagenesis in Trp53-deficient mice lacking inducible nitric oxide synthase gene

Masayuki Tatemichi, Hiroshi Tazawa, Mitsuharu Masuda, Mohammad Saleem, Sayori Wada, Lawrence A. Donehower, Hiroko Ohgaki, Hiroshi Ohshima

Journal:

International Journal of Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2004

12

Does p53 affect organismal aging?

Lawrence A. Donehower

Journal:

Journal of Cellular Physiology

Année:

2002

Langue:

english

Fichier:

PDF, 135 KB

english, 2002

13

Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice

Bonnie Nannenga, Xiongbin Lu, Melissa Dumble, Marc Van Maanen, Thuy-Ai Nguyen, Richard Sutton, T. Rajendra Kumar, Lawrence A. Donehower

Journal:

Molecular Carcinogenesis

Année:

2006

Langue:

english

Fichier:

PDF, 382 KB

english, 2006

14

Infrequent p53 mutations in 7,12-dimethylbenz[a]anthracene–induced mammary tumors in BALB/c and p53 hemizygous mice

D. Joseph Jerry, Janet S. Butel, Lawrence A. Donehower, Emily J. Paulson, Charles Cochran, Roger W. Wiseman, Daniel Medina

Journal:

Molecular Carcinogenesis

Année:

1994

Langue:

english

Fichier:

PDF, 804 KB

english, 1994

15

Effects of genetic background on tumorigenesis in p53-deficient mice

Lawrence A. Donehower, Michele Harvey, Hannes Vogel, Mark J. McArthur, Charles A. Montgomery Jr., Sang H. Park, Timothy Thompson, Richard J. Ford, Allan Bradley

Journal:

Molecular Carcinogenesis

Année:

1995

Langue:

english

Fichier:

PDF, 566 KB

english, 1995

16

Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models

Tamara Terzian, Melissa Dumble, Farinaz Arbab, Christina Thaller, Lawrence A Donehower, Guillermina Lozano, Monica J Justice, Dennis R Roop, Neil F Box

Journal:

The Journal of Pathology

Année:

2011

Langue:

english

Fichier:

PDF, 684 KB

english, 2011

17

Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas

Richard S. Morrison, Fumio Yamaguchi, Hideyuki Saya, Janet M. Bruner, Alan M. Yahanda, Lawrence A. Donehower, Mitchel Berger

Journal:

Journal of Neuro-Oncology

Année:

1994

Langue:

english

Fichier:

PDF, 947 KB

english, 1994

18

High susceptibility of nullizygous p53 knockout mice to colorectal tumor induction by 1,2-dimethylhydrazine

Hiroki Sakai, Tetsuya Tsukamoto, Masami Yamamoto, Norimitsu Shirai, Takeshi Iidaka, Akihiro Hirata, Tokuma Yanai, Toshiaki Masegi, Lawrence A. Donehower, Masae Tatematsu

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

2003

Langue:

english

Fichier:

PDF, 299 KB

english, 2003

19

P53 genotype as a determinant of ER expression and tamoxifen response in the MMTV-Wnt-1 model of mammary carcinogenesis

Robin Fuchs-Young, Stephanie H. Shirley, Isabel Lambertz, Jennifer K. L. Colby, Jie Tian, Dennis Johnston, Irma B. Gimenez-Conti, Lawrence A. Donehower, Claudio J. Conti, Stephen D. Hursting

Journal:

Breast Cancer Research and Treatment

Année:

2011

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2011

20

The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways

Xiongbin Lu, Thuy-Ai Nguyen, Sung-Hwan Moon, Yolanda Darlington, Matthias Sommer, Lawrence A. Donehower

Journal:

Cancer and Metastasis Reviews

Année:

2008

Langue:

english

Fichier:

PDF, 377 KB

english, 2008

21

Medulloblastomas overexpress the p53-inactivating oncogeneWIP1/PPM1D

Robert C. Castellino, Massimiliano De Bortoli, Xiongbin Lu, Sung-Hwan Moon, Thuy-Ai Nguyen, Mark A. Shepard, Pulivarthi H. Rao, Lawrence A. Donehower, John Y. H. Kim

Journal:

Journal of Neuro-Oncology

Année:

2008

Langue:

english

Fichier:

PDF, 534 KB

english, 2008

22

Organ-dependent susceptibility of p53 knockout mice to 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)

Akihiro Hirata, Tetsuya Tsukamoto, Masami Yamamoto, Shinji Takasu, Hiroki Sakai, Hisayo Ban, Tokuma Yanai, Toshiaki Masegi, Lawrence A. Donehower, Masae Tatematsu

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 292 KB

english, 2007

23

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

Jones, Stephen N., Roe, Amy E., Donehower, Lawrence A., Bradley, Allan

Journal:

Année:

1995

Fichier:

PDF, 838 KB

1995

24

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53–deficient mice

Harvey, Michele, Vogel, Hannes, Morris, Danna, Bradley, Allan, Bernstein, Alan, Donehower, Lawrence A.

Journal:

Nature Genetics

Année:

1995

Fichier:

PDF, 807 KB

1995

25

Spontaneous and carcinogen–induced tumorigenesis in p53–deficient mice

Harvey, Michele, McArthur, Mark J., Montgomery, Charles A., Butel, Janet S., Bradley, Allan, Donehower, Lawrence A.

Journal:

Nature Genetics

Année:

1993

Fichier:

PDF, 560 KB

1993

26

20 years studying p53 functions in genetically engineered mice

Donehower, Lawrence A., Lozano, Guillermina

Journal:

Nature Reviews Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 463 KB

english, 2009

27

Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressor

Frese, Kristopher K, Latorre, Isabel J, Chung, Sang-Hyuk, Caruana, Georgina, Bernstein, Alan, Jones, Stephen N, Donehower, Lawrence A, Justice, Monica J, Garner, Craig C, Javier, Ronald T

Journal:

The EMBO Journal

Année:

2006

Langue:

english

Fichier:

PDF, 394 KB

english, 2006

28

Mouse models in tumor suppression

Ghebranious, Nader, Donehower, Lawrence A

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 430 KB

english, 1999

29

Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression

Mussman, Jeffrey G, Horn, Henning F, Carroll, Patrick E, Okuda, Masaru, Tarapore, Pheruza, Donehower, Lawrence A, Fukasawa, Kenji

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 610 KB

english, 2000

30

Differential gene expression in mouse mammary adenocarcinomas in the presence and absence of wild type p53

Cui, Xian-Shu, Donehower, Lawrence A

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 415 KB

english, 2000

31

Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis

Moore, Lynette, Venkatachalam, Sundaresan, Vogel, Hannes, Watt, Julie C, Wu, Chao-Ling, Steinman, Heather, Jones, Stephen N, Donehower, Lawrence A

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 178 KB

english, 2003

32

Insights into Aging Obtained from p53 Mutant Mouse Models

MELISSA DUMBLE, CATHERINE GATZA, STUART TYNER, SUNDARESAN VENKATACHALAM, LAWRENCE A. DONEHOWER

Journal:

Annals of the New York Academy of Sciences

Année:

2004

Fichier:

PDF, 832 KB

2004

33

The p53-deficient mouse: a model for basic and applied cancer studies

Lawrence A. Donehower

Journal:

Seminars in Cancer Biology

Année:

1996

Langue:

english

Fichier:

PDF, 116 KB

english, 1996

34

Analysis of Human Immunodeficiency Virus Type 1 Integrase Mutants

M.Ali Ansari-Lari, Lawrence A. Donehower, Richard A. Gibbs

Journal:

Année:

1995

Fichier:

PDF, 284 KB

1995

35

Gene-targeting and the p53 tumor-suppressor gene

Arthur Sands, Lawrence A. Donehower, Allan Bradley

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1994

Langue:

english

Fichier:

PDF, 1.29 MB

english, 1994

36

The tumore suppressor p53

Lawrence A. Donehower, Allan Bradley

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Année:

1993

Langue:

english

Fichier:

PDF, 2.61 MB

english, 1993

37

Effects of p53 mutation on tumor progression: recent insights from mouse tumor models

Lawrence A. Donehower

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 592 KB

english, 1996

38

The Wip1 Phosphatase Acts as a Gatekeeper in the p53-Mdm2 Autoregulatory Loop

Xiongbin Lu, Ou Ma, Thuy-Ai Nguyen, Stephen N. Jones, Moshe Oren, Lawrence A. Donehower

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2007

39

The oncogenic phosphatase WIP1 negatively regulates nucleotide excision repair

Thuy-Ai Nguyen, Scott D. Slattery, Sung-Hwan Moon, Yolanda F. Darlington, Xiongbin Lu, Lawrence A. Donehower

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2010

40

p53: guardian AND suppressor of longevity?

Lawrence A. Donehower

Journal:

Experimental Gerontology

Année:

2005

Langue:

english

Fichier:

PDF, 70 KB

english, 2005

41

Aging-associated truncated form of p53 interacts with wild-type p53 and alters p53 stability, localization, and activity

Lynette Moore, Xiongbin Lu, Nader Ghebranious, Stuart Tyner, Lawrence A. Donehower

Journal:

Mechanisms of Ageing and Development

Année:

2007

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2007

42

Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging

George W. Hinkal, Catherine E. Gatza, Neha Parikh, Lawrence A. Donehower

Journal:

Mechanisms of Ageing and Development

Année:

2009

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2009

43

Probing p53 biological functions through the use of genetically engineered mouse models

Laura D. Attardi, Lawrence A. Donehower

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2005

Langue:

english

Fichier:

PDF, 180 KB

english, 2005

44

The utility of genetically altered mouse models for cancer research

Lawrence A. Donehower, John E. French, Stephen D. Hursting

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2005

Langue:

english

Fichier:

PDF, 113 KB

english, 2005

45

Activities of wildtype and mutant p53 in suppression of homologous recombination as measured by a retroviral vector system

Xiongbin Lu, Guillermina Lozano, Lawrence A. Donehower

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2003

Langue:

english

Fichier:

PDF, 358 KB

english, 2003

46

Murine tumor suppressor models

Sundaresan Venkatachalam, Lawrence A. Donehower

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1998

Langue:

english

Fichier:

PDF, 142 KB

english, 1998

47

Transgenic Animals in Toxicology

Thomas L. Goldsworthy, Leslie Recio, Ken Brown, Lawrence A. Donehower, Jon C. Mirsalis, Raymond W. Tennant, Iain F.H. Purchase

Journal:

Fundamental and Applied Toxicology

Année:

1994

Fichier:

PDF, 752 KB

1994

48

The Structure and Expression of the Murine Wildtype p53-Induced Phosphatase 1 (Wip1) Gene

Jene Choi, Ettore Appella, Lawrence A. Donehower

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 318 KB

english, 2000

49

Genomic organization of the mouse double minute 2 gene

Stephen N. Jones, M.Ali Ansari-Lari, Amy R. Hancock, William J. Jones, Richard A. Gibbs, Lawrence A. Donehower, Allan Bradley

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 427 KB

english, 1996

50

Lack of elevated liver carcinogenicity of aminophenylnorharman in p53-deficient mice

Takeshi Iidaka, Tetsuya Tsukamoto, Yukari Totsuka, Akihiro Hirata, Hiroki Sakai, Norimitsu Shirai, Masami Yamamoto, Keiji Wakabayashi, Tokuma Yanai, Toshiaki Masegi, Lawrence A. Donehower, Masae Tatem

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 475 KB

english, 2005